made|for|science GmbH

Publication bibliography

2021

Batkai, Sandor; Genschel, Celina; Viereck, Janika; Rump, Steffen; Bär, Christian; Borchert, Tobias et al. (2021): CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure. In Eur. Heart J. 42 (2), pp. 192–201
DOI: https://doi.org/10.1093/eurheartj/ehaa791
PMID: 33089304

König, Laura M.; Koller, Julia E.; Villinger, Karoline; Wahl, Deborah R.; Ziesemer, Katrin; Schupp, Harald T.; Renner, Britta (2021): Investigating the Relationship between Perceived Meal Colour Variety and Food Intake across Meal Types in a Smartphone-Based Ecological Momentary Assessment. In Nutrients 13 (3)
DOI: https://doi.org/10.3390/nu13030755
PMID: 33652759

2020

Dolch, Kerstin; Andrée, Sabine; Schwägele, Fredi (2020): Comparison of Real-Time PCR Quantification Methods in the Identification of Poultry Species in Meat Products. In Foods 9 (8)
DOI: https://doi.org/10.3390/foods9081049
PMID: 32756511

Foinquinos, Ariana; Batkai, Sandor; Genschel, Celina; Viereck, Janika; Rump, Steffen; Gyöngyösi, Mariann et al. (2020): Preclinical development of a miR-132 inhibitor for heart failure treatment. In Nat. Commun. 11 (1), p. 633
DOI: https://doi.org/10.1038/s41467-020-14349-2
PMID: 32005803

Juncheed, Kantida; Kohlstrunk, Bernd; Friebe, Sabrina; Dallacasagrande, Valentina; Maurer, Patric; Reichenbach, Andreas et al. (2020): Employing Nanostructured Scaffolds to Investigate the Mechanical Properties of Adult Mammalian Retinae Under Tension. In Int. J. Mol. Sci. 21 (11)
DOI: https://doi.org/10.3390/ijms21113889
PMID: 32485972

Maas, Paula; Grzegrzółka, Beata; Kreß, Philipp; Oberle, Martin; Judas, Michael; Kremer-Rücker, Prisca Valerie (2020): Prediction of body composition in mirror carp (Cyprinus carpio) by using linear measurements in vivo and computed tomography post-mortem. In Arch. Anim. Breed. 63 (1), pp. 69–80
DOI: https://doi.org/10.5194/aab-63-69-2020
PMID: 32175465

Mohanty, Sagarajit; Jyotsana, Nidhi; Sharma, Amit; Kloos, Arnold; Gabdoulline, Razif; Othman, Basem et al. (2020): Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia. In Cancers (Basel) 12 (10)
DOI: https://doi.org/10.3390/cancers12102766
PMID: 32993115

Ostendorf, Thomas; Zillinger, Thomas; Andryka, Katarzyna; Schlee-Guimaraes, Thais Marina; Schmitz, Saskia; Marx, Samira et al. (2020): Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2. In Immunity 52 (4), 591-605.e6
DOI: https://doi.org/10.1016/j.immuni.2020.03.009
PMID: 32294405

Wagner, Liane; Peukert, Manuela; Kranz, Bertolt; Gerhardt, Natalie; Andrée, Sabine; Busch, Ulrich; Brüggemann, Dagmar Adeline (2020): Comparison of Targeted (HPLC) and Nontargeted (GC-MS and NMR) Approaches for the Detection of Undeclared Addition of Protein Hydrolysates in Turkey Breast Muscle. In Foods 9 (8)
DOI: https://doi.org/10.3390/foods9081084
PMID: 32784468

Zoels, Susanne; Reiter, Simon; Ritzmann, Mathias; Weiß, Christine; Numberger, Jasmin; Schütz, Aneka et al. (2020): Influences of Immunocastration on Endocrine Parameters, Growth Performance and Carcass Quality, as Well as on Boar Taint and Penile Injuries. In Animals (Basel) 10 (2)
DOI: https://doi.org/10.3390/ani10020346
PMID: 32098237

2019

Brown, Jonathan M.; Dahlman, James E.; Neuman, Kristin K.; Prata, Carla A. H.; Krampert, Monika C.; Hadwiger, Philipp M.; Vornlocher, Hans-Peter (2019): Ligand Conjugated Multimeric siRNAs Enable Enhanced Uptake and Multiplexed Gene Silencing. In Nucleic Acid Ther. 29 (5), pp. 231–244
DOI: https://doi.org/10.1089/nat.2019.0782
PMID: 31393218

Jyotsana, Nidhi; Sharma, Amit; Chaturvedi, Anuhar; Budida, Ramachandramouli; Scherr, Michaela; Kuchenbauer, Florian et al. (2019): Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. In Ann. Hematol. 98 (8), pp. 1905–1918
DOI: https://doi.org/10.1007/s00277-019-03713-y
PMID: 31104089

Orlien, Vibeke; Bolumar, Tomas (2019): Biochemical and Nutritional Changes during Food Processing and Storage. In Foods 8 (10)
DOI: https://doi.org/10.3390/foods8100494
PMID: 31615038

2018

Jyotsana, N.; Sharma, A.; Chaturvedi, A.; Scherr, M.; Kuchenbauer, F.; Sajti, L. et al. (2018): RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo. In Leukemia 32 (1), pp. 224–226
DOI: https://doi.org/10.1038/leu.2017.269
PMID: 28827563

Meyer, Ingmar Sören; Goetzke, Carl Christoph; Kespohl, Meike; Sauter, Martina; Heuser, Arnd; Eckstein, Volker et al. (2018): Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis. In Front. Immunol. 9
DOI: https://doi.org/10.3389/fimmu.2018.02303
PMID: 30349538

Schöneweis, Katrin; Motter, Neil; Roppert, Pia L.; Lu, Mengji; Wang, Baoju; Roehl, Ingo et al. (2018): Activity of nucleic acid polymers in rodent models of HBV infection. In Antiviral Res. 149, pp. 26–33
DOI: https://doi.org/10.1016/j.antiviral.2017.10.022
PMID: 29126900

2017

Adler, Henry J.; Anbuhl, Kelsey L.; Atcherson, Samuel R.; Barlow, Nathan; Brennan, Marc A.; Brigande, John V. et al. (2017): Community network for deaf scientists. In Science 356 (6336), pp. 386–387
DOI: https://doi.org/10.1126/science.aan2330
PMID: 28450605

Heissig, Philipp; Schrimpf, Waldemar; Hadwiger, Philipp; Wagner, Ernst; Lamb, Don C. (2017): Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods. In PLoS ONE 12 (3), e0173401
DOI: https://doi.org/10.1371/journal.pone.0173401
PMID: 28278199

Roehl, Ingo; Seiffert, Stephan; Brikh, Celia; Quinet, Jonathan; Jamard, Catherine; Dorfler, Nadine et al. (2017): Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy. In Mol. Ther. Nucleic Acids 8, pp. 1–12
DOI: https://doi.org/10.1016/j.omtn.2017.04.019
PMID: 28918011

Vollmann, Elisabeth H.; Cao, Lizhi; Amatucci, Aldo; Reynolds, Taylor; Hamann, Stefan; Dalkilic-Liddle, Isin et al. (2017): Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. In Mol. Ther. Nucleic Acids 7, pp. 314–323
DOI: https://doi.org/10.1016/j.omtn.2017.04.014
PMID: 28624207

2016

Heissig, Philipp; Klein, Philipp M.; Hadwiger, Philipp; Wagner, Ernst (2016): DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization. In Mol. Ther. Nucleic Acids 5 (3), e288
DOI: https://doi.org/10.1038/mtna.2016.6
PMID: 26928236

Muckelbauer, Rebecca; Gortmaker, Steven L.; Libuda, Lars; Kersting, Mathilde; Clausen, Kerstin; Adelberger, Bettina; Müller-Nordhorn, Jacqueline (2016): Changes in water and sugar-containing beverage consumption and body weight outcomes in children. In Br. J. Nutr. 115 (11), pp. 2057–2066
DOI: https://doi.org/10.1017/S0007114516001136
PMID: 27040694

Parotat, S.; Holleben, K. von; Arnold, S.; Troeger, K.; Luecker, E. (2016): Hot-water spraying is a sensitive test for signs of life before dressing and scalding in pig abattoirs with carbon dioxide (CO2) stunning. In Animal 10 (2), pp. 326–332
DOI: https://doi.org/10.1017/S1751731115001573
PMID: 26289827

Real, Catherine Isabell; Lu, Mengji; Liu, Jia; Huang, Xuan; Trippler, Martin; Hossbach, Markus et al. (2016): Hepatitis B virus genome replication triggers toll-like receptor 3-dependent interferon responses in the absence of hepatitis B surface antigen. In Sci. Rep. 6, p. 24865
DOI: https://doi.org/10.1038/srep24865
PMID: 27121087

2015

Jagannath, Aarti; Hughes, Steven; Abdelgany, Amr; Pothecary, Carina A.; Di Pretoro, Simona; Pires, Susana S. et al. (2015): Isoforms of Melanopsin Mediate Different Behavioral Responses to Light. In Curr. Biol. 25 (18), pp. 2430–2434
DOI: https://doi.org/10.1016/j.cub.2015.07.071
PMID: 26320947

2014

Marschallinger, Julia; Krampert, Monika; Couillard-Despres, Sebastien; Heuchel, Rainer; Bogdahn, Ulrich; Aigner, Ludwig (2014): Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis. In Exp. Gerontol. 57 (100), pp. 149–154
DOI: https://doi.org/10.1016/j.exger.2014.05.011
PMID: 24862634

Martínez, Tamara; González, Maria Victoria; Roehl, Ingo; Wright, Natalia; Pañeda, Covadonga; Jiménez, Ana Isabel (2014): In vitro and in vivo efficacy of SYL040012, a novel siRNA compound for treatment of glaucoma. In Mol. Ther. 22 (1), pp. 81–91
DOI: https://doi.org/10.1038/mt.2013.216
PMID: 24025749

Massarrat, Sadegh; Haj-Sheykholeslami, Arghavan; Mohamadkhani, Ashraf; Zendehdel, Nasrin; Aliasgari, Ali; Rakhshani, Naser et al. (2014): Pepsinogen II can be a potential surrogate marker of morphological changes in corpus before and after H. pylori eradication. In Biomed Res. Int. 2014, p. 481607
DOI: https://doi.org/10.1155/2014/481607
PMID: 25028655

Schmidt, Carla; Grønborg, Mads; Deckert, Jochen; Bessonov, Sergey; Conrad, Thomas; Lührmann, Reinhard; Urlaub, Henning (2014): Mass spectrometry-based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. In RNA 20 (3), pp. 406–420
DOI: https://doi.org/10.1261/rna.041244.113
PMID: 24448447

2013

Ablasser, Andrea; Goldeck, Marion; Cavlar, Taner; Deimling, Tobias; Witte, Gregor; Röhl, Ingo et al. (2013): cGAS produces a 2’-5’-linked cyclic dinucleotide second messenger that activates STING. In Nature 498 (7454), pp. 380–384
DOI: https://doi.org/10.1038/nature12306
PMID: 23722158

Jagannath, Aarti; Butler, Rachel; Godinho, Sofia I. H.; Couch, Yvonne; Brown, Laurence A.; Vasudevan, Sridhar R. et al. (2013): The CRTC1-SIK1 pathway regulates entrainment of the circadian clock. In Cell 154 (5), pp. 1100–1111
DOI: https://doi.org/10.1016/j.cell.2013.08.004
PMID: 23993098

Wooddell, Christine I.; Rozema, David B.; Hossbach, Markus; John, Matthias; Hamilton, Holly L.; Chu, Qili et al. (2013): Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection. In Mol. Ther. 21 (5), pp. 973–985
DOI: https://doi.org/10.1038/mt.2013.31
PMID: 23439496

2012

Dohmen, Christian; Fröhlich, Thomas; Lächelt, Ulrich; Röhl, Ingo; Vornlocher, Hans-Peter; Hadwiger, Philipp; Wagner, Ernst (2012): Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing. In Mol. Ther. Nucleic Acids 1 (1), e7
DOI: https://doi.org/10.1038/mtna.2011.10
PMID: 23344624

Polach, Kevin J.; Matar, Majed; Rice, Jennifer; Slobodkin, Gregory; Sparks, Jeff; Congo, Richard et al. (2012): Delivery of siRNA to the mouse lung via a functionalized lipopolyamine. In Mol. Ther. 20 (1), pp. 91–100
DOI: https://doi.org/10.1038/mt.2011.210
PMID: 21988874

2011

Agafonov, Dmitry E.; Deckert, Jochen; Wolf, Elmar; Odenwälder, Peter; Bessonov, Sergey; Will, Cindy L. et al. (2011): Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. In Mol. Cell. Biol. 31 (13), pp. 2667–2682
DOI: https://doi.org/10.1128/MCB.05266-11
PMID: 21536652

2010

Krampert, Monika; Chirasani, Sridhar Reddy; Wachs, Frank-Peter; Aigner, Robert; Bogdahn, Ulrich; Yingling, Jonathan M. et al. (2010): Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner. In Mol. Cell. Biol. 30 (14), pp. 3685–3694
DOI: https://doi.org/10.1128/MCB.00434-09
PMID: 20479122

2009

Akinc, Akin; Goldberg, Michael; Qin, June; Dorkin, J. Robert; Gamba-Vitalo, Christina; Maier, Martin et al. (2009): Development of lipidoid-siRNA formulations for systemic delivery to the liver. In Mol. Ther. 17 (5), pp. 872–879
DOI: https://doi.org/10.1038/mt.2009.36
PMID: 19259063

Said, Nelly; Rieder, Renate; Hurwitz, Robert; Deckert, Jochen; Urlaub, Henning; Vogel, Jörg (2009): In vivo expression and purification of aptamer-tagged small RNA regulators. In Nucleic Acids Res. 37 (20), e133
DOI: https://doi.org/10.1093/nar/gkp719
PMID: 19726584

Wolf, Elmar; Kastner, Berthold; Deckert, Jochen; Merz, Christian; Stark, Holger; Lührmann, Reinhard (2009): Exon, intron and splice site locations in the spliceosomal B complex. In EMBO J. 28 (15), pp. 2283–2292
DOI: https://doi.org/10.1038/emboj.2009.171
PMID: 19536130

2008

Frank-Kamenetsky, Maria; Grefhorst, Aldo; Anderson, Norma N.; Racie, Timothy S.; Bramlage, Birgit; Akinc, Akin et al. (2008): Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. In Proc. Natl. Acad. Sci. U.S.A. 105 (33), pp. 11915–11920
DOI: https://doi.org/10.1073/pnas.0805434105
PMID: 18695239

Krampert, Monika; Heldin, Carl-Henrik; Heuchel, Rainer L. (2008): A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin. In Lab. Invest. 88 (11), pp. 1204–1214
DOI: https://doi.org/10.1038/labinvest.2008.81
PMID: 18762776

Prudêncio, Miguel; Rodrigues, Cristina D.; Hannus, Michael; Martin, Cécilie; Real, Eliana; Gonçalves, Lígia A. et al. (2008): Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection. In PLoS Pathog. 4 (11), e1000201
DOI: https://doi.org/10.1371/journal.ppat.1000201
PMID: 18989463

Rodrigues, Cristina D.; Hannus, Michael; Prudêncio, Miguel; Martin, Cécilie; Gonçalves, Lígia A.; Portugal, Sílvia et al. (2008): Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection. In Cell Host Microbe 4 (3), pp. 271–282
DOI: https://doi.org/10.1016/j.chom.2008.07.012
PMID: 18779053

2007

Behzadnia, Nastaran; Golas, Monika M.; Hartmuth, Klaus; Sander, Bjoern; Kastner, Berthold; Deckert, Jochen et al. (2007): Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. In EMBO J. 26 (6), pp. 1737–1748
DOI: https://doi.org/10.1038/sj.emboj.7601631
PMID: 17332742

John, Matthias; Constien, Rainer; Akinc, Akin; Goldberg, Michael; Moon, Young-Ah; Spranger, Martina et al. (2007): Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway. In Nature 449 (7163), pp. 745–747
DOI: https://doi.org/10.1038/nature06179
PMID: 17898712

2006

Braun, Susanne; Krampert, Monika; Bodó, Enikö; Kümin, Angelika; Born-Berclaz, Christiane; Paus, Ralf; Werner, Sabine (2006): Keratinocyte growth factor protects epidermis and hair follicles from cell death induced by UV irradiation, chemotherapeutic or cytotoxic agents. In J. Cell. Sci. 119 (Pt 23), pp. 4841–4849
DOI: https://doi.org/10.1242/jcs.03259
PMID: 17090603

Deckert, Jochen; Hartmuth, Klaus; Boehringer, Daniel; Behzadnia, Nastaran; Will, Cindy L.; Kastner, Berthold et al. (2006): Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. In Mol. Cell. Biol. 26 (14), pp. 5528–5543
DOI: https://doi.org/10.1128/MCB.00582-06
PMID: 16809785

Dybkov, Olexandr; Will, Cindy L.; Deckert, Jochen; Behzadnia, Nastaran; Hartmuth, Klaus; Lührmann, Reinhard (2006): U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. In Mol. Cell. Biol. 26 (7), pp. 2803–2816
DOI: https://doi.org/10.1128/MCB.26.7.2803-2816.2006
PMID: 16537922

Scherbel, Christina; Pichner, Rohtraud; Groschup, Martin H.; Mueller-Hellwig, Simone; Scherer, Siegfried; Dietrich, Richard et al. (2006): Degradation of scrapie associated prion protein (PrPSc) by the gastrointestinal microbiota of cattle. In Vet. Res. 37 (5), pp. 695–703
DOI: https://doi.org/10.1051/vetres:2006024
PMID: 16820134

2005

Krampert, Monika; Kuenzle, Sandra; Thai, Shelley N-M; Lee, Nathan; Iruela-Arispe, M. Luisa; Werner, Sabine (2005): ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells. In J. Biol. Chem. 280 (25), pp. 23844–23852
DOI: https://doi.org/10.1074/jbc.M412212200
PMID: 15843381

2004

Krampert, Monika; Bloch, Wilhelm; Sasaki, Takako; Bugnon, Philippe; Rülicke, Thomas; Wolf, Eckhard et al. (2004): Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. In Mol. Biol. Cell 15 (12), pp. 5242–5254
DOI: https://doi.org/10.1091/mbc.e04-02-0109
PMID: 15371548

2003

Frauendorf, Christian; Hausch, Felix; Röhl, Ingo; Lichte, Andrea; Vonhoff, Stefan; Klussmann, Sven (2003): Internal 32P-labeling of L-deoxyoligonucleotides. In Nucleic Acids Res. 31 (7), e34
DOI: https://doi.org/10.1093/nar/gng034
PMID: 12655022

2002

Pasparakis, Manolis; Courtois, Gilles; Hafner, Martin; Schmidt-Supprian, Marc; Nenci, Arianna; Toksoy, Atiye et al. (2002): TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. In Nature 417 (6891), pp. 861–866
DOI: https://doi.org/10.1038/nature00820
PMID: 12075355